In the next (27th) season of The Simpsons, Homer and Marge will become legally separated.

"In the premiere, it's discovered after all the years Homer has narcolepsy, and it's an incredible strain on the marriage," producer Al jean told Variety. "Homer and Marge legally separate, and Homer falls in love with his pharmacist, who's voiced by Lena Dunham."

Our in-house Simpsons expert recalls trying times in the Springfeild couple's past. Marge was courted by bowling instructor Jacques, following him back to his Fiesta Terraces apartment one evening. And in the 5th season, Homer finds himself attracted to the new girl at the plant where he works, Mindy Simmons.